Empty of Any Self-Nature

Regardless of what we view as the smallest and biggest entities in any given universe of discourse, the existence of each depends on the existence of the other. They either compose a larger entity or are themselves composed of smaller entities. In the material realm, the existence of specks of dust depends on the existence of the universe, and the existence of the universe depends on the existence of specks of dust. Thus, neither specks of dust nor the universe is real, for neither exists as an independent, permanent entity. And thus, all material things, however great or small they may be, are empty of any self-nature, and our view of them as real is essentially false.

---Red Pine, in his commentary on The Diamond Sutra---